Linear acral pseudolymphomatous angiokeratoma of children with associated nail dystrophy

Acral pseudolymphomatous angiokeratoma: case report and literature review*

The authors describe a case of a female patient with Acral Pseudolymphomatous Angiokeratoma of Children, known as APACHE. It is a rare benign cutaneous disease, of unknown etiology, characterized by multiple, asymptomatic erythematous-violaceous papules and nodules, usually located unilaterally with acral distribution. Today, this denomination is questionable, since there are published reports ...

Twenty nail dystrophy associated with lichen planus in a child: A case report

Twenty Nail Dystrophy (TND) is a rare acquired idiopathic nail dystrophy characterized by excess longitudinal ridging, distal notching, splitting, loss of nail luster and thinning of nail plates that may affect 1 to 20 nails. It occurs as a common manifestation of various dermatoses affecting the nail unit like lichen planus, psoriasis, atopic dermatitis, onychomycosis, vitiligo and alopecia ar...

A case of primary systemic amyloidosis with nail dystrophy

We hereby report a 79-year-old Iranian man presenting with nail dystrophy and subsequent development of purpuric and ecchymotic plaques, hemorrhagic bullae, and infiltrated papules on the head, neck and trunk. Histological examination of the gingiva, bone marrow aspiration, and biopsy confirmed the diagnosis of primary systemic amyloidosis. In this case, nail dystrophy was the presenting sign o...

Congenital hereditary endothelial dystrophy associated with nail hypoplasia.

Papular angiolymphoid hyperplasia and lymphoplasmacytic plaque: a clinical and histological spectrum.

Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rare form of cutaneous pseudolymphoma characterized byangiomatous papules with a predilection for the acral regions of children. Classically, a dense dermal lymphocytic infiltrate composed of both T and B cells is seen in histological specimens, together with prominent vessels lined by plump endothelial cells. Increasing evidence ...